biopython

Quick Review

Excellent bioinformatics skill with comprehensive coverage of Biopython's molecular biology toolkit. The description clearly articulates when to use this skill versus alternatives (gget, bioservices). SKILL.md provides outstanding structure with a well-organized index to 7 reference files covering all major domains (sequence I/O, alignment, BLAST, databases, structures, phylogenetics, advanced features). Task knowledge is exceptional with quick examples for each module, common patterns, best practices, and troubleshooting guidance. The modular organization keeps SKILL.md concise while promising detailed documentation in referenced files. Novelty is strong: batch processing, custom pipelines, and BLAST automation would be token-intensive for a CLI agent alone. The skill meaningfully reduces complexity for multi-step bioinformatics workflows. Minor deduction on novelty only because some simple sequence operations might be straightforward without the skill, but overall this is a highly valuable, well-structured bioinformatics resource.