clinpgx-database

Quick Review

Exceptional pharmacogenomics skill with comprehensive coverage of ClinPGx API capabilities. The description clearly defines when to use the skill across clinical decision support, drug safety, and precision medicine scenarios. Task knowledge is outstanding with detailed API endpoints, complete workflow examples (clinical prescription support, gene panel analysis, drug safety assessment, population pharmacogenomics, literature review), rate limiting implementation, error handling, and caching patterns. Structure is excellent with logical organization from overview through core capabilities to workflows and best practices, though SKILL.md is quite lengthy. Novelty is strong - accessing specialized pharmacogenomics data (gene-drug interactions, CPIC guidelines, allele functions, drug labels) would be token-intensive and error-prone for a CLI agent alone, requiring domain expertise in both API usage and clinical pharmacogenetics. The skill provides significant value by consolidating authoritative sources (PharmGKB, CPIC, PharmCAT, DPWG, FDA) into accessible queries with proper clinical context. Referenced files (query_clinpgx.py, api_reference.md) appropriately delegate implementation details and comprehensive API documentation.