geo-database

Quick Review

Excellent skill for accessing NCBI GEO database. The description clearly covers capabilities (search, download, retrieve datasets/files). Task knowledge is comprehensive with extensive working code examples for GEOparse, E-utilities, FTP access, data analysis, batch processing, and meta-analysis. Structure is logical with well-organized sections, though the SKILL.md is quite lengthy - some advanced analysis code could potentially be moved to separate files. Novelty is strong: while basic GEO queries are possible via CLI tools, the integrated workflows for batch processing, differential expression analysis, meta-analysis across studies, and handling complex data formats (SOFT, MINiML, series matrices) would require significant token investment and domain expertise for a CLI agent to replicate. The skill meaningfully reduces complexity for transcriptomics researchers by providing ready-to-use patterns for common genomics workflows.