reactome-database

Quick Review

Excellent bioinformatics skill providing comprehensive coverage of Reactome pathway analysis capabilities. The description clearly articulates when and how to use the skill for pathway enrichment, gene mapping, and expression analysis. Task knowledge is strong with detailed code examples for both REST API and Python package usage, covering overrepresentation analysis, expression data submission, and result visualization. Structure is well-organized with clear sections, though SKILL.md is somewhat lengthy (could benefit from moving more details to referenced files). Novelty is solid - while pathway queries are conceptually straightforward, the skill meaningfully simplifies a specialized bioinformatics workflow that would require significant domain knowledge and API familiarity for a general CLI agent. The comprehensive examples, token management guidance, and integration of both Content and Analysis services provide substantial value for systems biology research tasks.