scikit-bio

Quick Review

Exceptional bioinformatics skill with comprehensive coverage of scikit-bio capabilities. The description clearly articulates when to use this skill, covering 10 major capability areas (sequence manipulation, alignment, phylogenetics, diversity analysis, ordination, statistical testing, I/O, distance matrices, biological tables, protein embeddings) with practical code examples for each. The structure is excellent with a logical flow from overview to capabilities to best practices, and appropriate delegation of detailed API specs to the references file. The skill provides substantial novelty by packaging complex bioinformatics workflows (microbiome analysis, phylogenetic reconstruction, diversity metrics, statistical testing) that would require many tokens and domain expertise for a CLI agent to implement from scratch. Minor room for improvement in explicitly stating input/output formats for invocation scenarios, but overall this is a production-ready skill that meaningfully reduces complexity for biological data analysis tasks.