scikit-bio

Quick Review

Excellent bioinformatics skill with comprehensive coverage of scikit-bio capabilities. The SKILL.md provides detailed, well-organized documentation across 10 core capability areas with practical code examples for each. The description clearly articulates when to use the skill, and the extensive code patterns enable a CLI agent to invoke functionality confidently. Task knowledge is outstanding, covering sequence analysis, alignments, phylogenetics, diversity metrics, ordination, statistical testing, and file I/O with sufficient detail for implementation. Structure is logical with clear section delineation and cross-references to API documentation. The skill addresses a genuinely complex domain (bioinformatics/microbiome analysis) that would require significant tokens for a CLI agent to implement from scratch, making it highly novel and cost-effective. Minor room for improvement in making some technical concepts even more accessible to non-specialists, but overall this is a high-quality, production-ready skill.